Correlation between embryological factors and pregnancy rate: Development of an embryo score in a cryopreservation programme

Miquel Solé; Josep Santaló; Ignacio Rodríguez; Montse Boada; Buenaventura Coroleu; Pere N. Barri; Anna Veiga

doi:10.1007/s10815-010-9498-0

Correlation between embryological factors and pregnancy rate: Development of an embryo score in a cryopreservation programme

Miquel Solé, Josep Santaló, Ignacio Rodríguez, Montse Boada, Buenaventura Coroleu, Pere N. Barri, Anna Veiga

Department of Cellular Biology, Physiology and Immunology

Research output: Contribution to journal › Article › Research › peer-review

30 Citations (Scopus)

Abstract

Purpose: To establish which embryo parameters, in frozen thawed embryo transfers, have the highest prognosis value in the establishment of pregnancy. The relative importance of different embryo parameters is used to develop an embryo score. Methods: Retrospective analysis of the implantation rate in 356 frozen/thawed single embryo transfers. A logistic regression model is used to establish an embryo score. Results: A direct correlation is established between the implantation rate and fresh embryo development (number of blastomeres and their symmetry), survival rate after thawing and mitosis resumption after overnight culture. Conclusions: An embryo score is developed to determine the implantation potential of frozen/thawed embryos. © 2010 Springer Science+Business Media, LLC.

Original language	English
Pages (from-to)	129-136
Journal	Journal of Assisted Reproduction and Genetics
Volume	28
DOIs	https://doi.org/10.1007/s10815-010-9498-0
Publication status	Published - 1 Feb 2011

Keywords

Cryopreserved embryos
Embryo score
Embryological parameters
Single embryo transfer

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10.1007/s10815-010-9498-0

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title = "Correlation between embryological factors and pregnancy rate: Development of an embryo score in a cryopreservation programme",

abstract = "Purpose: To establish which embryo parameters, in frozen thawed embryo transfers, have the highest prognosis value in the establishment of pregnancy. The relative importance of different embryo parameters is used to develop an embryo score. Methods: Retrospective analysis of the implantation rate in 356 frozen/thawed single embryo transfers. A logistic regression model is used to establish an embryo score. Results: A direct correlation is established between the implantation rate and fresh embryo development (number of blastomeres and their symmetry), survival rate after thawing and mitosis resumption after overnight culture. Conclusions: An embryo score is developed to determine the implantation potential of frozen/thawed embryos. {\textcopyright} 2010 Springer Science+Business Media, LLC.",

keywords = "Cryopreserved embryos, Embryo score, Embryological parameters, Single embryo transfer",

author = "Miquel Sol{\'e} and Josep Santal{\'o} and Ignacio Rodr{\'i}guez and Montse Boada and Buenaventura Coroleu and Barri, {Pere N.} and Anna Veiga",

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T1 - Correlation between embryological factors and pregnancy rate: Development of an embryo score in a cryopreservation programme

AU - Solé, Miquel

AU - Santaló, Josep

AU - Rodríguez, Ignacio

AU - Boada, Montse

AU - Coroleu, Buenaventura

AU - Barri, Pere N.

AU - Veiga, Anna

PY - 2011/2/1

Y1 - 2011/2/1

N2 - Purpose: To establish which embryo parameters, in frozen thawed embryo transfers, have the highest prognosis value in the establishment of pregnancy. The relative importance of different embryo parameters is used to develop an embryo score. Methods: Retrospective analysis of the implantation rate in 356 frozen/thawed single embryo transfers. A logistic regression model is used to establish an embryo score. Results: A direct correlation is established between the implantation rate and fresh embryo development (number of blastomeres and their symmetry), survival rate after thawing and mitosis resumption after overnight culture. Conclusions: An embryo score is developed to determine the implantation potential of frozen/thawed embryos. © 2010 Springer Science+Business Media, LLC.

AB - Purpose: To establish which embryo parameters, in frozen thawed embryo transfers, have the highest prognosis value in the establishment of pregnancy. The relative importance of different embryo parameters is used to develop an embryo score. Methods: Retrospective analysis of the implantation rate in 356 frozen/thawed single embryo transfers. A logistic regression model is used to establish an embryo score. Results: A direct correlation is established between the implantation rate and fresh embryo development (number of blastomeres and their symmetry), survival rate after thawing and mitosis resumption after overnight culture. Conclusions: An embryo score is developed to determine the implantation potential of frozen/thawed embryos. © 2010 Springer Science+Business Media, LLC.

KW - Cryopreserved embryos

KW - Embryo score

KW - Embryological parameters

KW - Single embryo transfer

U2 - 10.1007/s10815-010-9498-0

DO - 10.1007/s10815-010-9498-0

M3 - Article

SN - 1058-0468

VL - 28

SP - 129

EP - 136

JO - Journal of Assisted Reproduction and Genetics

JF - Journal of Assisted Reproduction and Genetics

ER -

Correlation between embryological factors and pregnancy rate: Development of an embryo score in a cryopreservation programme

Abstract

Keywords

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