Correlation between embryological factors and pregnancy rate: Development of an embryo score in a cryopreservation programme

Miquel Solé, Josep Santaló, Ignacio Rodríguez, Montse Boada, Buenaventura Coroleu, Pere N. Barri, Anna Veiga

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Abstract

Purpose: To establish which embryo parameters, in frozen thawed embryo transfers, have the highest prognosis value in the establishment of pregnancy. The relative importance of different embryo parameters is used to develop an embryo score. Methods: Retrospective analysis of the implantation rate in 356 frozen/thawed single embryo transfers. A logistic regression model is used to establish an embryo score. Results: A direct correlation is established between the implantation rate and fresh embryo development (number of blastomeres and their symmetry), survival rate after thawing and mitosis resumption after overnight culture. Conclusions: An embryo score is developed to determine the implantation potential of frozen/thawed embryos. © 2010 Springer Science+Business Media, LLC.
Original languageEnglish
Pages (from-to)129-136
JournalJournal of Assisted Reproduction and Genetics
Volume28
DOIs
Publication statusPublished - 1 Feb 2011

Keywords

  • Cryopreserved embryos
  • Embryo score
  • Embryological parameters
  • Single embryo transfer

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