Two new copper(II) complexes with the bronchodilator Clenbuterol (HL) have been synthesized: the binuclear complex Cu2L2Cl 2·4DMSO (1) and the mononuclear CuL2· 2CH3OH (2) and have been studied using electronic, IR and EPR spectra, magnetochemical, thermogravimetric and single-crystal X-ray diffraction methods. Each of the Cu(II) centres in the binuclear complex 1 is four coordinated by one terminal chlorine and one nitrogen atom, and by two bridging oxygen atoms from two different ligand molecules. Each molecule of the binuclear complex also links four DMSO molecules by hydrogen bonds of the types S = O⋯H2N and S = O⋯HN. The overall structure is built by sheets of Cu2L2Cl2, parallel to the ab plane, separated by layers of DMSO. In the mononuclear moiety 2, Cu(II) is coordinated bidentately with the N and O atoms of two Clenbuterol ligands, forming a nearly square-planar complex CuL2. Two CH3OH molecules are also incorporated in the unit cell, forming hydrogen bonds between the hydroxyl hydrogen atom of CH3OH and the oxygen atoms of the ligands, CH 3OH⋯O(1). Both structures correlate well with the spectral, magnetochemical and thermal behaviour of complexes 1 and 2. © 2005 Elsevier Ltd. All rights reserved.
|Publication status||Published - 27 Oct 2005|
- Binuclear complex
- Cu(II) complexes
- Magnetochemical properties
- X-ray data