Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013

Esther Fondevilla; Santiago Grau; Sergi Mojal; Mercedes Palomar; Lurdes Matas; Francesc Gudiol; Antònia Balet; Montserrat Pons; Maria Teresa Barrera; Miquel Calafell; Gemma Enrique-Tarancon; Glòria Gayolà; Montserrat Carrascossa; Camilla Valls; Mireia Fuster; Ludivina Ibáñez; Jordi Cuquet; Maria Sagalés; Mònica Calonge; Lídia Salse; Juan Serrais; Ester López-Suñé; Susana Terré; Teresa Arranz; Marisa Grañó; Mercè Guixa; Francesc Pàez; Susana Terré; Ana Ayestaran; Leonor Munell; Virginia Gol; Edurne Fernández De Gamarra; Lluís Campins; Teresa Gurrera; Núria Bosacoma; Elisenda Flotats; Anisi Morón; Mònica Gómez; Olga Curiel; Maria José Fraile; Conxita Mestres; Natàlia Carrasco; Mercè Espona; Esther Vicente; Pilar Marcos; Anna Capellà; Begoña Pascual; Paula Arcenillas; Pablo March; Magda Montserrat; Jordi Fernández; Núria Benages; Eugènia Òdena; Marta Isern; Pilar Alemany; Francesca Pujol; Núria San Juan; Laura Losa; Isabel Martínez; Pilar Capdevila; Inma Molins; Laura Canadell; Santiago Manuel Cano; Ariadna Padullés; Laura Gratacós; David Campany; Margarida Garau; Ramon Borràs; Pilar Salvador; Ana Gómez; Maria Esther Julián; Josana Fierro; Maria Àngels Vidal; Josep Maria Calbet

doi:10.1586/14787210.2016.1096776

Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013

Esther Fondevilla, Santiago Grau, Sergi Mojal, Mercedes Palomar, Lurdes Matas, Francesc Gudiol, Antònia Balet, Montserrat Pons, Maria Teresa Barrera, Miquel Calafell, Gemma Enrique-Tarancon, Glòria Gayolà, Montserrat Carrascossa, Camilla Valls, Mireia Fuster, Ludivina Ibáñez, Jordi Cuquet, Maria Sagalés, Mònica Calonge, Lídia SalseJuan Serrais, Ester López-Suñé, Susana Terré, Teresa Arranz, Marisa Grañó, Mercè Guixa, Francesc Pàez, Susana Terré, Ana Ayestaran, Leonor Munell, Virginia Gol, Edurne Fernández De Gamarra, Lluís Campins, Teresa Gurrera, Núria Bosacoma, Elisenda Flotats, Anisi Morón, Mònica Gómez, Olga Curiel, Maria José Fraile, Conxita Mestres, Natàlia Carrasco, Mercè Espona, Esther Vicente, Pilar Marcos, Anna Capellà, Begoña Pascual, Paula Arcenillas, Pablo March, Magda Montserrat, Jordi Fernández, Núria Benages, Eugènia Òdena, Marta Isern, Pilar Alemany, Francesca Pujol, Núria San Juan, Laura Losa, Isabel Martínez, Pilar Capdevila, Inma Molins, Laura Canadell, Santiago Manuel Cano, Ariadna Padullés, Laura Gratacós, David Campany, Margarida Garau, Ramon Borràs, Pilar Salvador, Ana Gómez, Maria Esther Julián, Josana Fierro, Maria Àngels Vidal, Josep Maria Calbet

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Abstract

© 2015 Taylor & Francis. Objective To know the patterns and consumption trends (2008-2013) of antifungal agents for systemic use in 52 acute care hospitals affiliated to VINCat Program in Catalonia (Spain). Methods Consumption was calculated in defined daily doses (DDD)/100 patient-days and analyzed according to hospital size and complexity and clinical departments. Results Antifungal consumption was higher in intensive care units (ICU) (14.79) than in medical (3.08) and surgical departments (1.19). Fluconazole was the most consumed agent in all type of hospitals and departments. Overall antifungal consumption increased by 20.5%during the study period (p = 0.066); a significant upward trend was observed in the consumption of both azoles and echinocandins. In ICUs, antifungal consumption increased by 12.4% (p = 0.019). Conclusions The study showed a sustained increase in the overall consumption of systemic antifungals in a large number of acute care hospitals of different characteristics in Catalonia. In ICUs there was a trend towards the substitution of older agents by the new ones.

Original language	English
Pages (from-to)	137-144
Journal	Expert Review of Anti-Infective Therapy
Volume	14
Issue number	1
DOIs	https://doi.org/10.1586/14787210.2016.1096776
Publication status	Published - 2 Jan 2016

Keywords

Antifungal consumption
Antimycotic use
Azoles
Echinocandins
Fluconazole

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10.1586/14787210.2016.1096776

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Fondevilla, E., Grau, S., Mojal, S., Palomar, M., Matas, L., Gudiol, F., Balet, A., Pons, M., Barrera, M. T., Calafell, M., Enrique-Tarancon, G., Gayolà, G., Carrascossa, M., Valls, C., Fuster, M., Ibáñez, L., Cuquet, J., Sagalés, M., Calonge, M., ... Calbet, J. M. (2016). Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013. Expert Review of Anti-Infective Therapy, 14(1), 137-144. https://doi.org/10.1586/14787210.2016.1096776

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title = "Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013",

abstract = "{\textcopyright} 2015 Taylor & Francis. Objective To know the patterns and consumption trends (2008-2013) of antifungal agents for systemic use in 52 acute care hospitals affiliated to VINCat Program in Catalonia (Spain). Methods Consumption was calculated in defined daily doses (DDD)/100 patient-days and analyzed according to hospital size and complexity and clinical departments. Results Antifungal consumption was higher in intensive care units (ICU) (14.79) than in medical (3.08) and surgical departments (1.19). Fluconazole was the most consumed agent in all type of hospitals and departments. Overall antifungal consumption increased by 20.5%during the study period (p = 0.066); a significant upward trend was observed in the consumption of both azoles and echinocandins. In ICUs, antifungal consumption increased by 12.4% (p = 0.019). Conclusions The study showed a sustained increase in the overall consumption of systemic antifungals in a large number of acute care hospitals of different characteristics in Catalonia. In ICUs there was a trend towards the substitution of older agents by the new ones.",

keywords = "Antifungal consumption, Antimycotic use, Azoles, Echinocandins, Fluconazole",

author = "Esther Fondevilla and Santiago Grau and Sergi Mojal and Mercedes Palomar and Lurdes Matas and Francesc Gudiol and Ant{\`o}nia Balet and Montserrat Pons and Barrera, {Maria Teresa} and Miquel Calafell and Gemma Enrique-Tarancon and Gl{\`o}ria Gayol{\`a} and Montserrat Carrascossa and Camilla Valls and Mireia Fuster and Ludivina Ib{\'a}{\~n}ez and Jordi Cuquet and Maria Sagal{\'e}s and M{\`o}nica Calonge and L{\'i}dia Salse and Juan Serrais and Ester L{\'o}pez-Su{\~n}{\'e} and Susana Terr{\'e} and Teresa Arranz and Marisa Gra{\~n}{\'o} and Merc{\`e} Guixa and Francesc P{\`a}ez and Susana Terr{\'e} and Ana Ayestaran and Leonor Munell and Virginia Gol and {De Gamarra}, {Edurne Fern{\'a}ndez} and Llu{\'i}s Campins and Teresa Gurrera and N{\'u}ria Bosacoma and Elisenda Flotats and Anisi Mor{\'o}n and M{\`o}nica G{\'o}mez and Olga Curiel and Fraile, {Maria Jos{\'e}} and Conxita Mestres and Nat{\`a}lia Carrasco and Merc{\`e} Espona and Esther Vicente and Pilar Marcos and Anna Capell{\`a} and Bego{\~n}a Pascual and Paula Arcenillas and Pablo March and Magda Montserrat and Jordi Fern{\'a}ndez and N{\'u}ria Benages and Eug{\`e}nia {\`O}dena and Marta Isern and Pilar Alemany and Francesca Pujol and Juan, {N{\'u}ria San} and Laura Losa and Isabel Mart{\'i}nez and Pilar Capdevila and Inma Molins and Laura Canadell and Cano, {Santiago Manuel} and Ariadna Padull{\'e}s and Laura Gratac{\'o}s and David Campany and Margarida Garau and Ramon Borr{\`a}s and Pilar Salvador and Ana G{\'o}mez and Juli{\'a}n, {Maria Esther} and Josana Fierro and Vidal, {Maria {\`A}ngels} and Calbet, {Josep Maria}",

year = "2016",

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doi = "10.1586/14787210.2016.1096776",

language = "English",

volume = "14",

pages = "137--144",

journal = "Expert Review of Anti-Infective Therapy",

issn = "1478-7210",

publisher = "Taylor and Francis Ltd.",

number = "1",

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Fondevilla, E, Grau, S, Mojal, S, Palomar, M, Matas, L, Gudiol, F, Balet, A, Pons, M, Barrera, MT, Calafell, M, Enrique-Tarancon, G, Gayolà, G, Carrascossa, M, Valls, C, Fuster, M, Ibáñez, L, Cuquet, J, Sagalés, M, Calonge, M, Salse, L, Serrais, J, López-Suñé, E, Terré, S, Arranz, T, Grañó, M, Guixa, M, Pàez, F, Terré, S, Ayestaran, A, Munell, L, Gol, V, De Gamarra, EF, Campins, L, Gurrera, T, Bosacoma, N, Flotats, E, Morón, A, Gómez, M, Curiel, O, Fraile, MJ, Mestres, C, Carrasco, N, Espona, M, Vicente, E, Marcos, P, Capellà, A, Pascual, B, Arcenillas, P, March, P, Montserrat, M, Fernández, J, Benages, N, Òdena, E, Isern, M, Alemany, P, Pujol, F, Juan, NS, Losa, L, Martínez, I, Capdevila, P, Molins, I, Canadell, L, Cano, SM, Padullés, A, Gratacós, L, Campany, D, Garau, M, Borràs, R, Salvador, P, Gómez, A, Julián, ME, Fierro, J, Vidal, MÀ & Calbet, JM 2016, 'Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013', Expert Review of Anti-Infective Therapy, vol. 14, no. 1, pp. 137-144. https://doi.org/10.1586/14787210.2016.1096776

TY - JOUR

T1 - Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013

AU - Fondevilla, Esther

AU - Grau, Santiago

AU - Mojal, Sergi

AU - Palomar, Mercedes

AU - Matas, Lurdes

AU - Gudiol, Francesc

AU - Balet, Antònia

AU - Pons, Montserrat

AU - Barrera, Maria Teresa

AU - Calafell, Miquel

AU - Enrique-Tarancon, Gemma

AU - Gayolà, Glòria

AU - Carrascossa, Montserrat

AU - Valls, Camilla

AU - Fuster, Mireia

AU - Ibáñez, Ludivina

AU - Cuquet, Jordi

AU - Sagalés, Maria

AU - Calonge, Mònica

AU - Salse, Lídia

AU - Serrais, Juan

AU - López-Suñé, Ester

AU - Terré, Susana

AU - Arranz, Teresa

AU - Grañó, Marisa

AU - Guixa, Mercè

AU - Pàez, Francesc

AU - Terré, Susana

AU - Ayestaran, Ana

AU - Munell, Leonor

AU - Gol, Virginia

AU - De Gamarra, Edurne Fernández

AU - Campins, Lluís

AU - Gurrera, Teresa

AU - Bosacoma, Núria

AU - Flotats, Elisenda

AU - Morón, Anisi

AU - Gómez, Mònica

AU - Curiel, Olga

AU - Fraile, Maria José

AU - Mestres, Conxita

AU - Carrasco, Natàlia

AU - Espona, Mercè

AU - Vicente, Esther

AU - Marcos, Pilar

AU - Capellà, Anna

AU - Pascual, Begoña

AU - Arcenillas, Paula

AU - March, Pablo

AU - Montserrat, Magda

AU - Fernández, Jordi

AU - Benages, Núria

AU - Òdena, Eugènia

AU - Isern, Marta

AU - Alemany, Pilar

AU - Pujol, Francesca

AU - Juan, Núria San

AU - Losa, Laura

AU - Martínez, Isabel

AU - Capdevila, Pilar

AU - Molins, Inma

AU - Canadell, Laura

AU - Cano, Santiago Manuel

AU - Padullés, Ariadna

AU - Gratacós, Laura

AU - Campany, David

AU - Garau, Margarida

AU - Borràs, Ramon

AU - Salvador, Pilar

AU - Gómez, Ana

AU - Julián, Maria Esther

AU - Fierro, Josana

AU - Vidal, Maria Àngels

AU - Calbet, Josep Maria

PY - 2016/1/2

Y1 - 2016/1/2

N2 - © 2015 Taylor & Francis. Objective To know the patterns and consumption trends (2008-2013) of antifungal agents for systemic use in 52 acute care hospitals affiliated to VINCat Program in Catalonia (Spain). Methods Consumption was calculated in defined daily doses (DDD)/100 patient-days and analyzed according to hospital size and complexity and clinical departments. Results Antifungal consumption was higher in intensive care units (ICU) (14.79) than in medical (3.08) and surgical departments (1.19). Fluconazole was the most consumed agent in all type of hospitals and departments. Overall antifungal consumption increased by 20.5%during the study period (p = 0.066); a significant upward trend was observed in the consumption of both azoles and echinocandins. In ICUs, antifungal consumption increased by 12.4% (p = 0.019). Conclusions The study showed a sustained increase in the overall consumption of systemic antifungals in a large number of acute care hospitals of different characteristics in Catalonia. In ICUs there was a trend towards the substitution of older agents by the new ones.

AB - © 2015 Taylor & Francis. Objective To know the patterns and consumption trends (2008-2013) of antifungal agents for systemic use in 52 acute care hospitals affiliated to VINCat Program in Catalonia (Spain). Methods Consumption was calculated in defined daily doses (DDD)/100 patient-days and analyzed according to hospital size and complexity and clinical departments. Results Antifungal consumption was higher in intensive care units (ICU) (14.79) than in medical (3.08) and surgical departments (1.19). Fluconazole was the most consumed agent in all type of hospitals and departments. Overall antifungal consumption increased by 20.5%during the study period (p = 0.066); a significant upward trend was observed in the consumption of both azoles and echinocandins. In ICUs, antifungal consumption increased by 12.4% (p = 0.019). Conclusions The study showed a sustained increase in the overall consumption of systemic antifungals in a large number of acute care hospitals of different characteristics in Catalonia. In ICUs there was a trend towards the substitution of older agents by the new ones.

KW - Antifungal consumption

KW - Antimycotic use

KW - Azoles

KW - Echinocandins

KW - Fluconazole

U2 - 10.1586/14787210.2016.1096776

DO - 10.1586/14787210.2016.1096776

M3 - Article

SN - 1478-7210

VL - 14

SP - 137

EP - 144

JO - Expert Review of Anti-Infective Therapy

JF - Expert Review of Anti-Infective Therapy

IS - 1

ER -

Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013

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Keywords

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