Consumption of systemic antifungal agents among acute care hospitals in Catalonia (Spain), 2008-2013

Esther Fondevilla, Santiago Grau, Sergi Mojal, Mercedes Palomar, Lurdes Matas, Francesc Gudiol, Antònia Balet, Montserrat Pons, Maria Teresa Barrera, Miquel Calafell, Gemma Enrique-Tarancon, Glòria Gayolà, Montserrat Carrascossa, Camilla Valls, Mireia Fuster, Ludivina Ibáñez, Jordi Cuquet, Maria Sagalés, Mònica Calonge, Lídia SalseJuan Serrais, Ester López-Suñé, Susana Terré, Teresa Arranz, Marisa Grañó, Mercè Guixa, Francesc Pàez, Susana Terré, Ana Ayestaran, Leonor Munell, Virginia Gol, Edurne Fernández De Gamarra, Lluís Campins, Teresa Gurrera, Núria Bosacoma, Elisenda Flotats, Anisi Morón, Mònica Gómez, Olga Curiel, Maria José Fraile, Conxita Mestres, Natàlia Carrasco, Mercè Espona, Esther Vicente, Pilar Marcos, Anna Capellà, Begoña Pascual, Paula Arcenillas, Pablo March, Magda Montserrat, Jordi Fernández, Núria Benages, Eugènia Òdena, Marta Isern, Pilar Alemany, Francesca Pujol, Núria San Juan, Laura Losa, Isabel Martínez, Pilar Capdevila, Inma Molins, Laura Canadell, Santiago Manuel Cano, Ariadna Padullés, Laura Gratacós, David Campany, Margarida Garau, Ramon Borràs, Pilar Salvador, Ana Gómez, Maria Esther Julián, Josana Fierro, Maria Àngels Vidal, Josep Maria Calbet

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4 Citations (Scopus)

Abstract

© 2015 Taylor & Francis. Objective To know the patterns and consumption trends (2008-2013) of antifungal agents for systemic use in 52 acute care hospitals affiliated to VINCat Program in Catalonia (Spain). Methods Consumption was calculated in defined daily doses (DDD)/100 patient-days and analyzed according to hospital size and complexity and clinical departments. Results Antifungal consumption was higher in intensive care units (ICU) (14.79) than in medical (3.08) and surgical departments (1.19). Fluconazole was the most consumed agent in all type of hospitals and departments. Overall antifungal consumption increased by 20.5%during the study period (p = 0.066); a significant upward trend was observed in the consumption of both azoles and echinocandins. In ICUs, antifungal consumption increased by 12.4% (p = 0.019). Conclusions The study showed a sustained increase in the overall consumption of systemic antifungals in a large number of acute care hospitals of different characteristics in Catalonia. In ICUs there was a trend towards the substitution of older agents by the new ones.
Original languageEnglish
Pages (from-to)137-144
JournalExpert Review of Anti-Infective Therapy
Volume14
Issue number1
DOIs
Publication statusPublished - 2 Jan 2016

Keywords

  • Antifungal consumption
  • Antimycotic use
  • Azoles
  • Echinocandins
  • Fluconazole

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