Consensus document. Management of non-alcoholic fatty liver disease (NAFLD). Clinical practice guideline

Rocío Aller, Conrado Fernández-Rodríguez, Oreste lo Iacono, Rafael Bañares, Javier Abad, José Antonio Carrión, Carmelo García-Monzón, Joan Caballería, Marina Berenguer, Manuel Rodríguez-Perálvarez, José López Miranda, Eduardo Vilar-Gómez, Javier Crespo, Miren García-Cortés, María Reig, José María Navarro, Rocío Gallego, Joan Genescà, María Teresa Arias-Loste, María Jesús ParejaAgustín Albillos, Jordi Muntané, Francisco Jorquera, Elsa Solà, Manuel Hernández-Guerra, Miguel Ángel Rojo, Javier Salmerón, Llorenc Caballería, Moisés Diago, Esther Molina, Ramón Bataller, Manuel Romero-Gómez

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36 Citations (Scopus)


© 2018 Elsevier España, S.L.U. Non-alcoholic fatty liver disease (NAFLD) is the main cause of liver diseases in Spain and the incidence is raising due to the outbreak of type 2 diabetes and obesity. This CPG suggests recommendation about diagnosis, mainly non-invasive biomarkers, and clinical management of this entity. Life-style modifications to achieve weight loss is the main target in the management of NAFLD. Low caloric Mediterranean diet and 200 minutes/week of aerobic exercise are encouraged. In non-responders patients with morbid obesity, bariatric surgery or metabolic endoscopy could be indicated. Pharmacological therapy is indicated in patients with NASH and fibrosis and non-responders to weight loss measures. NAFLD could influence liver transplantation, as a growing indication, the impact of steatosis in the graft viability, de novo NAFLD rate after OLT and a raised cardiovascular risk that modify the management of this entity. The current CPG was the result of the First Spanish NAFLD meeting in Seville.
Original languageEnglish
Pages (from-to)328-349
JournalGastroenterologia y Hepatologia
Issue number5
Publication statusPublished - 1 May 2018


  • Cardiovascular risk
  • Clinical guidelines
  • Diagnosis
  • Fibrosis
  • Non-alcoholic fatty liver disease
  • Recommendations
  • Steatosis
  • Treatment


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