Using 1D and 2D NMR spectra, the compounds obtained, in a mixture, in the reaction of glycerol with iodine were identified as the two isomers (cis and trans) of 2-iodomethyl-5-hydroxymethyl-1,4-dioxane and the two isomers (cis and trans) of 2-iodomethyl-6-hydroxymethyl-1,4-dioxane. Thus, the composition of the pharmaceutical formulation named IPG has finally been established.
|Journal||Magnetic Resonance in Chemistry|
|Publication status||Published - 1 Jun 1996|
- 13 C NMR
- 1 H NMR
- Gradient-enhanced 2D NMR