Appropriate therapy for severe acute pancreatitis is currently an unresolved goal. 20% of patients affected by acute pancreatitis present numerous complications, localized as well as systemic, with high mortality. It is fundamental to isolate severe cases in order to indicate monitoring and treatment in intensive care units for early detection and treatment of multiple organ failure. It is currently accepted that, in its acute phase, surgery of pancreatitis should be restricted to localized complications of the disease, for the most part septic. Indiscriminate primary intervention for acute pancreatitis is associated with a higher morbimortality rate of over 60%. Even early multiple organ failure with no demonstrated infection does not benefit from surgical treatment. In diagnoses of pancreatic infection, necrosectomy, debridement and open drainage of the abdominal cavity are associated with lower mortality (12%) but also with recurrent infection and the need for re-operation. Were intervention is indicated numerous complications continue to be detected that are associated with pancreatitis as well as with the surgical treatment employed. The most frequent of these are residual or recurrent infection, hemorrhage, necrosis and intestinal and pancreatic fistulas, frequently contributing to multiple organ failure and death.
|Publication status||Published - 1 Jan 2001|
- Severe acute pancreatitis
- Surgical treatment