Comparison of commensal and clinical isolates for diversity of plasmids in Escherichia coli and Klebsiella pneumoniae

Judith Rodríguez-Navarro, Elisenda Miró, Maryury Brown-Jaque, Juan Carlos Hurtado, Albert Moreno, Maite Muniesa, Juan José González-López, Jordi Vila, Paula Espinal*, Ferran Navarro

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

Abstract

In this study, the plasmid content of clinical and commensal strains was analyzed and compared. The replicon profile was similar in both populations, except for L, M, A/C, and N (detected only in clinical strains) and HI1 (only in commensal strains). Although I1 and F were the most frequent replicons, only IncI1, sequence type 12 (ST12) was associated with blaCMY-2 in both populations. In contrast, the widespread resistant IncF plasmids were not linked to a single epidemic plasmid.

Original languageEnglish
Article numbere02064-19
JournalAntimicrobial Agents and Chemotherapy
Volume64
Issue number5
DOIs
Publication statusPublished - May 2020

Keywords

  • Antimicrobial resistance
  • Enterobacteriaceae
  • Plasmid epidemiology
  • PMLST
  • Replicon

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