Comb-like models for transport along spiny dendrites

Vicenç Méndez, Alexander Iomin

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)


We suggest a modification of a comb model to describe anomalous transport in spiny dendrites. Geometry of the comb structure consisting of a one-dimensional backbone and lateral branches makes it possible to describe anomalous diffusion, where dynamics inside fingers corresponds to spines, while the backbone describes diffusion along dendrites. The presented analysis establishes that the fractional dynamics in spiny dendrites is controlled by fractal geometry of the comb structure and fractional kinetics inside the spines. Our results show that the transport along spiny dendrites is subdiffusive and depends on the density of spines in agreement with recent experiments. © 2013 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)46-51
JournalChaos, Solitons and Fractals
Publication statusPublished - 17 Jun 2013


Dive into the research topics of 'Comb-like models for transport along spiny dendrites'. Together they form a unique fingerprint.

Cite this