Cognitive rehabilitation in acquired brain injury: Variables mediating treatment response

A. García-Molina, R. López-Blázquez, A. García-Rudolph, R. Sánchez-Carrión, A. Enseñat-Cantallops, J. M. Tormos, T. Roig-Rovira

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    © 2014 Elsevier España, S.L.U. and SERMEF. All rights reserved. Objective To identify the variables related to response to a cognitive rehabilitation program in a population of patients with acquired brain injury. Material and methods This retrospective study included 528 patients with acquired brain injury who received cognitive rehabilitation at our center between February 2008 and January 2013. We used logistic regression analysis to examine the impact of predictive variables on treatment response (dependent variable). Differences between pre- and post-treatment neuropsychological assessment were used to calculate treatment response in the domains of attention, memory, and executive function. Results For the attention index, the variables positively associated with better treatment response were age at the time of injury (OR = 0.97, 95% CI: 0.96-0.98) and place of treatment (OR = 0.45, 95% CI: 0.27-0.73). For the memory index, the variables positively associated with better treatment response were age (OR = 0.98, 95% CI: 0.96 to 0.99), etiology (OR = 0.63, 95% CI: 0.39 to 1) and place of treatment (OR = 0.48, 95% CI: 0.29 to 0.79); these variables were also significant for the executive index. Conclusions These findings suggest that part of the inter-individual differences in response to cognitive rehabilitation in patients with acquired brain injury could be explained by age, etiology and place of treatment.
    Original languageEnglish
    Pages (from-to)144-149
    JournalRehabilitacion
    Volume49
    Issue number3
    DOIs
    Publication statusPublished - 1 Jan 2015

    Keywords

    • Brain injury
    • Cognitive disorders
    • Logistic models
    • Odds ratio
    • Rehabilitation

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