C<inf>sp</inf>3-F bond activation by nucleophilic attack of the {Pt <inf>2</inf>S<inf>2</inf>} core assisted by non-covalent interactions

Ainara Nova; Rubén Mas-Ballesté; Gregori Ujaque; Pilar González-Duarte; Agustí Lledós

doi:10.1039/b801889h

C<inf>sp</inf>3-F bond activation by nucleophilic attack of the {Pt <inf>2</inf>S<inf>2</inf>} core assisted by non-covalent interactions

Ainara Nova, Rubén Mas-Ballesté, Gregori Ujaque, Pilar González-Duarte, Agustí Lledós

Department of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

25 Citations (Scopus)

Abstract

The high nucleophilicity of the sulfur atoms in [Pt2(dppp) 2(μ-S)2] triggers a C-F activation process in 1,3-difluoro-2-propanol that leads to the [Pt2(dppp) 2(μ-S)(μ-SCH2CH(OH)CH2F]F product through a SN2 mechanism, where the O-H⋯F hydrogen bond established from the alcohol group of the organic substrate is essential for assisting the departure of the fluoride anion. © The Royal Society of Chemistry.

Original language	English
Pages (from-to)	3130-3132
Journal	Chemical Communications
Issue number	27
DOIs	https://doi.org/10.1039/b801889h
Publication status	Published - 8 Jul 2008

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title = "Csp3-F bond activation by nucleophilic attack of the {Pt 2S2} core assisted by non-covalent interactions",

abstract = "The high nucleophilicity of the sulfur atoms in [Pt2(dppp) 2(μ-S)2] triggers a C-F activation process in 1,3-difluoro-2-propanol that leads to the [Pt2(dppp) 2(μ-S)(μ-SCH2CH(OH)CH2F]F product through a SN2 mechanism, where the O-H⋯F hydrogen bond established from the alcohol group of the organic substrate is essential for assisting the departure of the fluoride anion. {\textcopyright} The Royal Society of Chemistry.",

author = "Ainara Nova and Rub{\'e}n Mas-Ballest{\'e} and Gregori Ujaque and Pilar Gonz{\'a}lez-Duarte and Agust{\'i} Lled{\'o}s",

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doi = "10.1039/b801889h",

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T1 - Csp3-F bond activation by nucleophilic attack of the {Pt 2S2} core assisted by non-covalent interactions

AU - Nova, Ainara

AU - Mas-Ballesté, Rubén

AU - Ujaque, Gregori

AU - González-Duarte, Pilar

AU - Lledós, Agustí

PY - 2008/7/8

Y1 - 2008/7/8

N2 - The high nucleophilicity of the sulfur atoms in [Pt2(dppp) 2(μ-S)2] triggers a C-F activation process in 1,3-difluoro-2-propanol that leads to the [Pt2(dppp) 2(μ-S)(μ-SCH2CH(OH)CH2F]F product through a SN2 mechanism, where the O-H⋯F hydrogen bond established from the alcohol group of the organic substrate is essential for assisting the departure of the fluoride anion. © The Royal Society of Chemistry.

AB - The high nucleophilicity of the sulfur atoms in [Pt2(dppp) 2(μ-S)2] triggers a C-F activation process in 1,3-difluoro-2-propanol that leads to the [Pt2(dppp) 2(μ-S)(μ-SCH2CH(OH)CH2F]F product through a SN2 mechanism, where the O-H⋯F hydrogen bond established from the alcohol group of the organic substrate is essential for assisting the departure of the fluoride anion. © The Royal Society of Chemistry.

U2 - 10.1039/b801889h

DO - 10.1039/b801889h

M3 - Article

SP - 3130

EP - 3132

IS - 27

ER -

C<inf>sp</inf>3-F bond activation by nucleophilic attack of the {Pt <inf>2</inf>S<inf>2</inf>} core assisted by non-covalent interactions

Abstract

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