Clonality analysis by HUMARA assay in Spanish females with essential thrombocythemia and polycythemia vera

Lurdes Zamora, Lourdes Florensa, Carles Besses, Beatriz Bellosillo, Francesc Solé

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Abstract

Analysis of the human androgen receptor gene (HUMARA) allows clonality to be assessed in essential thrombocythemia (ET) and polycythemia vera (PV). We studied clonality in 44 patients with ET, 18 with PV and in 64 healthy controls. The X-chromosome inactivation pattern was analyzed by HUMARA-polymerase chain reaction on DNA from purified granulocytes, T lymphocytes and the CD3 - fraction of mononuclear cells.
Original languageEnglish
Pages (from-to)259-261
JournalHaematologica
Volume90
Issue number2
Publication statusPublished - 1 Feb 2005

Keywords

  • Clonality
  • Essential thrombocythemia
  • Humara
  • Polycythemia vera

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