Clinical differences between cocaine-dependent patients with and without antisocial personality disorder

Marina Comín, Santiago Redondo, Constanza Daigre, Lara Grau-López, Miguel Casas, Carlos Roncero

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)


© 2016 Elsevier Ireland Ltd The aim of this study is to compare the features of two groups of cocaine dependent patients in treatment, one of them with co-morbid diagnosis of antisocial personality disorder and the other not. Cross-sectional design, with 143 cocaine-dependent patients attending a drug unit, distributed in two groups: patients with and without Antisocial Personality Disorder. As results, we found that the 15.38% of the sample were diagnosed with an Antisocial Personality Disorder. In relation to socio-demographic variables, Antisocial Personality Disorder patients have less probability of being working or studying (9.1% vs. 47.9%). After multivariate analysis it was found that significantly Antisocial Personality Disorder patients have more opiates dependence (OR: 0.219; 95% IC 0.072–0.660), sedative dependence (OR: 0.203; 95% IC 0.062–0.644) and in more cases show Borderline Personality Disorder (OR: 0.239; 95% IC 0.077–0.746). This study highlights significant differences between cocaine addicts with or without an Antisocial Personality Disorder. All these differences are good indicators of the complexity of the patients with this personality disorder. Better knowledge of their profile will help us to improve the design of specific treatment programs.
Original languageEnglish
Pages (from-to)587-592
JournalPsychiatry Research
Publication statusPublished - 30 Dec 2016


  • Addiction
  • Addiction severity
  • Antisocial personality disorder
  • Cocaine dependence
  • Dual diagnosis


Dive into the research topics of 'Clinical differences between cocaine-dependent patients with and without antisocial personality disorder'. Together they form a unique fingerprint.

Cite this