Translocaciones cromosómicas en los sarcomas de partes blandas: De la biología molecular a la aplicación clínica

Translated title of the contribution: Chromosomal translocations in soft tissue sarcomas: From molecular biology to clinical application

J. Roma, A. Masià, A. Almazán-Moga, M. Rebull, P. Velasco, S. Gallego, J. Sánchez De Toledo*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Recent advances in the knowledge of the molecular biology of paediatric sarcomas, especially the characterisation of chromosomal translocations associated specifically with particular types of cancer, have established bases for the introduction of new diagnostic tools. This article reviews the main chromosomal translocations associated with paediatric tumours, and summarises their molecular characteristics regarding their oncogenic capabilities, possible usefulness as a differential diagnostic tools and possible correlation with clinical parameters.

Translated title of the contributionChromosomal translocations in soft tissue sarcomas: From molecular biology to clinical application
Original languageSpanish
Pages (from-to)103.e1-103.e7
JournalAnales de Pediatria
Volume76
Issue number2
DOIs
Publication statusPublished - Feb 2012

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