Chromosomal aberration analysis in 85 control individuals

E. Carbonell; F. Peris; N. Xamena; A. Creus; R. Marcos

doi:10.1016/S0165-1218(96)90124-X

Chromosomal aberration analysis in 85 control individuals

E. Carbonell, F. Peris, N. Xamena, A. Creus, R. Marcos

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Abstract

Chromosomal aberrations (CA) were studied in the peripheral blood lymphocytes of 85 healthy male volunteers from Barcelona (Catalonia, Spain). The effect that factors such as age, life style, work exposure and medical treatment had on the cytological endpoints was studied by means of a Poisson regression model. The results obtained indicate a significant positive relationship between the age of the subjects analyzed and the total of chromosome-type aberrations. With respect to the other variables analyzed, a positive association was found between the frequent consumption of analgesics and the incidence of chromatid-type aberrations.

Original language	English
Pages (from-to)	29-37
Journal	Mutation Research - Genetic Toxicology
Volume	370
Issue number	1
DOIs	https://doi.org/10.1016/S0165-1218(96)90124-X
Publication status	Published - 15 Aug 1996

Keywords

Chromosomal aberration
Human lymphocyte

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10.1016/S0165-1218(96)90124-X

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title = "Chromosomal aberration analysis in 85 control individuals",

abstract = "Chromosomal aberrations (CA) were studied in the peripheral blood lymphocytes of 85 healthy male volunteers from Barcelona (Catalonia, Spain). The effect that factors such as age, life style, work exposure and medical treatment had on the cytological endpoints was studied by means of a Poisson regression model. The results obtained indicate a significant positive relationship between the age of the subjects analyzed and the total of chromosome-type aberrations. With respect to the other variables analyzed, a positive association was found between the frequent consumption of analgesics and the incidence of chromatid-type aberrations.",

keywords = "Chromosomal aberration, Human lymphocyte",

author = "E. Carbonell and F. Peris and N. Xamena and A. Creus and R. Marcos",

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T1 - Chromosomal aberration analysis in 85 control individuals

AU - Carbonell, E.

AU - Peris, F.

AU - Xamena, N.

AU - Creus, A.

AU - Marcos, R.

PY - 1996/8/15

Y1 - 1996/8/15

N2 - Chromosomal aberrations (CA) were studied in the peripheral blood lymphocytes of 85 healthy male volunteers from Barcelona (Catalonia, Spain). The effect that factors such as age, life style, work exposure and medical treatment had on the cytological endpoints was studied by means of a Poisson regression model. The results obtained indicate a significant positive relationship between the age of the subjects analyzed and the total of chromosome-type aberrations. With respect to the other variables analyzed, a positive association was found between the frequent consumption of analgesics and the incidence of chromatid-type aberrations.

AB - Chromosomal aberrations (CA) were studied in the peripheral blood lymphocytes of 85 healthy male volunteers from Barcelona (Catalonia, Spain). The effect that factors such as age, life style, work exposure and medical treatment had on the cytological endpoints was studied by means of a Poisson regression model. The results obtained indicate a significant positive relationship between the age of the subjects analyzed and the total of chromosome-type aberrations. With respect to the other variables analyzed, a positive association was found between the frequent consumption of analgesics and the incidence of chromatid-type aberrations.

KW - Chromosomal aberration

KW - Human lymphocyte

U2 - 10.1016/S0165-1218(96)90124-X

DO - 10.1016/S0165-1218(96)90124-X

M3 - Article

SN - 0165-1218

VL - 370

SP - 29

EP - 37

JO - Mutation Research - Genetic Toxicology Testing and Biomonitoring of Environmental or Occupational Exposure

JF - Mutation Research - Genetic Toxicology Testing and Biomonitoring of Environmental or Occupational Exposure

IS - 1

ER -

Chromosomal aberration analysis in 85 control individuals

Abstract

Keywords

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