We have used fluorescence in situ hybridization (FISH) with a biotinylated cosmid probe (13q14) to screen 25 unrelated cases with bilateral retinoblastoma and one case with unilateral retinoblastoma. In 25 cases no deletion or chromosome rearrangements were found. One constitutional mutation resulting from a de novo balanced chromosome translocation (5:13) in a patient with bilateral retinoblastoma was detected.
|Journal||Cancer Genetics and Cytogenetics|
|Publication status||Published - 1 Jul 1997|
Triviño, E., Guitart, M., Egozcue, J., Coll, M. D., & Querol Murillo, E. (1997). Characterization by FISH of a t(5;13) in a patient with bilateral retinoblastoma. Cancer Genetics and Cytogenetics, 96, 23-25. https://doi.org/10.1016/S0165-4608(97)89572-6