TY - JOUR
T1 - Characteristics and treatment patterns of patients with asthma on multiple-inhaler triple therapy in Spain
AU - Barrecheguren, Miriam
AU - Monteagudo, Mònica
AU - Miravitlles, Marc
AU - Flor Escriche, Xavier
AU - Núñez, Alexa
AU - Osorio, Jeisson
AU - Muñoz Gall, Xavier
AU - Ojanguren, Iñigo
PY - 2022
Y1 - 2022
N2 - The aim of this observational, retrospective study was to describe characteristics, treatment patterns, and adherence among patients with asthma who initiated multiple-inhaler triple therapy (MITT) in Catalonia, Spain. This study used data of patients initiating MITT in 2016 from the SIDIAP (Information System for Research in Primary Care) database, which covers ~80% of the Catalonian population (5.8 million). Of 1,204 patients initiating MITT, 361 (30.0%) stepped down (discontinued ≥ 1 and continued ≥1 MITT component) and 89 (7.4%) stopped all three components of MITT for a period of 60 days during the following 12 months. In the follow-up period, 196 (16.3%) patients were considered adherent to MITT (>0.8 proportion of days covered [PDC]), with a mean (standard deviation) PDC of 0.52 (0.51) days. Given the low adherence and substantial rates of step down/discontinuation among patients initiating MITT, there is an urgent need to implement strategies to improve treatment adherence/persistence.
AB - The aim of this observational, retrospective study was to describe characteristics, treatment patterns, and adherence among patients with asthma who initiated multiple-inhaler triple therapy (MITT) in Catalonia, Spain. This study used data of patients initiating MITT in 2016 from the SIDIAP (Information System for Research in Primary Care) database, which covers ~80% of the Catalonian population (5.8 million). Of 1,204 patients initiating MITT, 361 (30.0%) stepped down (discontinued ≥ 1 and continued ≥1 MITT component) and 89 (7.4%) stopped all three components of MITT for a period of 60 days during the following 12 months. In the follow-up period, 196 (16.3%) patients were considered adherent to MITT (>0.8 proportion of days covered [PDC]), with a mean (standard deviation) PDC of 0.52 (0.51) days. Given the low adherence and substantial rates of step down/discontinuation among patients initiating MITT, there is an urgent need to implement strategies to improve treatment adherence/persistence.
KW - Asthma
KW - Diseases
U2 - 10.1038/s41533-022-00270-2
DO - 10.1038/s41533-022-00270-2
M3 - Article
C2 - 35273167
SN - 2055-1010
VL - 32
JO - npj Primary Care Respiratory Medicine
JF - npj Primary Care Respiratory Medicine
ER -