Cervical metastasis of squamous cell carcinoma of unknown origin: experience at Hospital de Sant Pau, Barcelona, Spain

A. Jürgens Mestre, M. Quer Agusti, D. Agudelo García, E. Trías Mis, X. León Vintro, A. López Pousa, M. Vega Masana, P. de las Heras Durán, J. Burgués Vila

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Abstract

Between 1984 and 1992, 18 cases of cervical metastasis of squamous cell or anaplastic carcinoma (1% of all head and neck tumors) were seen at the Hospital de la Santa Creu i Sant Pau (Barcelona, Spain). Fifteen patients underwent radical surgery: 1 N1, 4 N2A and 10N3, N1 and N2A patients underwent surgery followed by radiotherapy. The 10 N3 patients began with neoadjuvant chemotherapy (cisplatin and 5-fluorouracil), then 8 had radical neck dissection and 2 had palliative radiotherapy. The primary tumor was found in 11%. The 5-year survival rate was 40% in N1+2A and 11% in N3. Chemotherapy did not improve survival in advanced disease, but it facilitated neck dissection and selection of the group with the prognosis.
Original languageEnglish
Pages (from-to)233-238
JournalActa otorrinolaringológica española
Volume47
Issue number3
Publication statusPublished - 1 Jan 1996

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