Ceftolozane-tazobactam for the treatment of ventilator-associated infections by colistin-resistant Pseudomonas aeruginosa

Francisco Álvarez Lerma, Rosana Muñoz Bermudez, Santiago Grau, María Pilar Gracia Arnillas, Luisa Sorli, Lluis Recasens, Miquel Mico García

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9 Citations (Scopus)

Abstract

© 2017, Sociedad Espanola de Quiminoterapia. All rights reserved. The use of colistin for the treatment of multiresistant bacteria has led to the emergence of colistin-resistant strains of Gram-negative bacilli. Treatment of infections caused by these pan–drug-resistant bacteria is difficult owing to the paucity of effective antibiotics. We report two cases of ventilator-associated respiratory infection caused by pan–drug-resistant, colistin-resistant Pseudomonas aeruginosa that were successfully treated with ceftolozane-tazobactam.
Original languageEnglish
Pages (from-to)224-228
JournalRevista Espanola de Quimioterapia
Volume30
Issue number3
Publication statusPublished - 1 Jun 2017

Keywords

  • Ceftolozane-tazobactam
  • Colistin-resistant pseudomonas aeruginosa
  • ICU
  • Ventilator-associated respiratory infection

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