Caudoventral abdominal lymphangiosarcoma in a cat treated with metronomic chemotherapy

Jorge Castro-López, Nuria Bermúdez, Jorge Martínez, José Ramos-Varas, Marta Planellas, Josep Pastor

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

© 2013 British Veterinary Association. All rights reserved. A 10-year-old, male neutered domestic shorthair cat was referred for reddish discolouration of its abdominal skin with serosanguineous discharge. The affected skin was bruised, nodular and had fluid-filled cavities. It was painful on palpation. A final diagnosis of lymphangiosarcoma was made by prospero-related homeobox gene-1 (PROX-1) immunohistochemistry. Metronomic chemotherapy treatment was instaured with toceranib phosphate, chlorambucil and meloxicam. Partial remission was achieved at 18 days and stable disease was maintained for 36 days (survival time: 54 days). Afterward, the tumour began to regrow aggressively and the patient developed anorexia; owners elected for euthanasia. Total survival time achieved was 63 days. To the authors' knowledge, this is the first case report of feline caudoventral abdominal lymphangiosarcoma treated with metronomic chemotherapy.
Original languageEnglish
Article numbere000020
JournalVeterinary Record Case Reports
Volume1
DOIs
Publication statusPublished - 1 Dec 2013

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