Catalytic cross-coupling of diazo compounds with coinage metal-based catalysts: An experimental and theoretical study

Ivan Rivilla, W. M.C. Sameera, Eleuterio Alvarez, M. Mar Díaz-Requejo, Feliu Maseras, Pedro J. Pérez

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Abstract

We examined the ability of TpxM (Tpx = hydrotris(pyrazolyl)borate ligand; M = Cu and Ag) and IPrMCl (IPr = 1,3-bis(diisopropylphenyl)imidazol-2-ylidene; M = Cu, Ag, Au) complexes as catalyst precursors for the cross-coupling of diazo compounds. Experimental data showed that the metal centre can be tuned with the appropriate selection of the ligand to yield either the homo- or hetero-coupling (cross-coupling) products. A computational study of the reaction mechanism allowed the rationalization of the experimental reactivity patterns, and the identification of the key reaction step controlling the selectivity: the initial reaction between the metallocarbene intermediate and one of the diazo compounds. © 2013 The Royal Society of Chemistry.
Original languageEnglish
Pages (from-to)4132-4138
JournalDalton Transactions
Volume42
Issue number12
DOIs
Publication statusPublished - 28 Mar 2013

Fingerprint Dive into the research topics of 'Catalytic cross-coupling of diazo compounds with coinage metal-based catalysts: An experimental and theoretical study'. Together they form a unique fingerprint.

Cite this