Cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy

Carlos Jericó, Hernando Knobel, Alexia Carmona, M. Luisa Sorli, José Luis López-Colomés, Juan Pedro-Botet

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Abstract

BACKGROUND AND OBJECTIVE: Our goal was to assess the main characteristics of cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy (HAART). PATIENTS AND METHOD: Retrospective analysis of the clinico-epidemiological characteristics of 16 HIV-infected patients treated with HAART who had suffered a cardiovascular event from a 1,459 patients' cohort. RESULTS: Clinical presentation of cardiovascular disease was an acute coronary syndrome in 12 cases, ischemic stroke in 2 and peripheral vascular disease in 2. Patients included in the study had a mean of 3.2 cardiovascular risk factors, smoking and low HDL levels being the more prevalent risk factors. Eight (50%, 95% CI, 25-75%) patients fulfilled the criteria of metabolic syndrome. The mean CD4 count was 548 × 106/l. CONCLUSIONS: HIV-infected patients on HAART have a high cardiovascular risk. A strict managemet of modifiable risk factors must be warranted in these patients.
Original languageEnglish
Pages (from-to)298-300
JournalMedicina Clinica
Volume122
Issue number8
DOIs
Publication statusPublished - 6 Mar 2004

Keywords

  • Antiretroviral therapy
  • Cardiovascular disease
  • Cardiovascular risk
  • HIV infection
  • Secondary prevention

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    Jericó, C., Knobel, H., Carmona, A., Sorli, M. L., López-Colomés, J. L., & Pedro-Botet, J. (2004). Cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy. Medicina Clinica, 122(8), 298-300. https://doi.org/10.1157/13058678