Carcinoid tumor of the thymus associated with Cushing's syndrome and dysgeusia: Case report and review of the literature

Cristina Claret, Juan J. Chillarón, Juana A. Flores, David Benaiges, Rafael Aguiló, Mar García, Guadalupe Aguilar, Alberto Goday, Juan F. Cano-Pérez

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Abstract

A 30-year-old man was hospitalized with edema, polyuria, and abnormalities in taste. ACTH and cortisol levels at admission were markedly elevated, even after attempted suppression with 8 mg dexamethasone. A thoracic-abdominal CT revealed an anterior mediastinal lesion and hyperplasia of both adrenal glands. After excision of the mediastinal mass, which confirmed the presence of a carcinoid thymic tumor, the patient became totally asymptomatic, with normal ACTH and cortisol levels. A carcinoid thymic tumor has a poor prognosis, especially when it is associated with Cushing's syndrome. Most patients will present recidivism or metastasis within 5 years after surgery. However, the low number of cases available for analysis makes it difficult to establish optimum therapeutic approaches. © 2009 Humana Press.
Original languageEnglish
Pages (from-to)1-5
JournalEndocrine
Volume37
Issue number1
DOIs
Publication statusPublished - 1 Feb 2010

Keywords

  • Carcinoid
  • Cushing's syndrome
  • Neuroendocrine tumors
  • Thymus

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