Carcinoid tumor of the thymus associated with Cushing's syndrome and dysgeusia: Case report and review of the literature

Cristina Claret; Juan J. Chillarón; Juana A. Flores; David Benaiges; Rafael Aguiló; Mar García; Guadalupe Aguilar; Alberto Goday; Juan F. Cano-Pérez

doi:10.1007/s12020-009-9249-0

Carcinoid tumor of the thymus associated with Cushing's syndrome and dysgeusia: Case report and review of the literature

Cristina Claret, Juan J. Chillarón, Juana A. Flores, David Benaiges, Rafael Aguiló, Mar García, Guadalupe Aguilar, Alberto Goday, Juan F. Cano-Pérez

Department of Surgery

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Abstract

A 30-year-old man was hospitalized with edema, polyuria, and abnormalities in taste. ACTH and cortisol levels at admission were markedly elevated, even after attempted suppression with 8 mg dexamethasone. A thoracic-abdominal CT revealed an anterior mediastinal lesion and hyperplasia of both adrenal glands. After excision of the mediastinal mass, which confirmed the presence of a carcinoid thymic tumor, the patient became totally asymptomatic, with normal ACTH and cortisol levels. A carcinoid thymic tumor has a poor prognosis, especially when it is associated with Cushing's syndrome. Most patients will present recidivism or metastasis within 5 years after surgery. However, the low number of cases available for analysis makes it difficult to establish optimum therapeutic approaches. © 2009 Humana Press.

Original language	English
Pages (from-to)	1-5
Journal	Endocrine
Volume	37
Issue number	1
DOIs	https://doi.org/10.1007/s12020-009-9249-0
Publication status	Published - 1 Feb 2010

Keywords

Carcinoid
Cushing's syndrome
Neuroendocrine tumors
Thymus

Access to Document

10.1007/s12020-009-9249-0

Fingerprint Dive into the research topics of 'Carcinoid tumor of the thymus associated with Cushing's syndrome and dysgeusia: Case report and review of the literature'. Together they form a unique fingerprint.

Cite this

@article{5d29952979e54b0dbe94201e647c89f7,

title = "Carcinoid tumor of the thymus associated with Cushing's syndrome and dysgeusia: Case report and review of the literature",

abstract = "A 30-year-old man was hospitalized with edema, polyuria, and abnormalities in taste. ACTH and cortisol levels at admission were markedly elevated, even after attempted suppression with 8 mg dexamethasone. A thoracic-abdominal CT revealed an anterior mediastinal lesion and hyperplasia of both adrenal glands. After excision of the mediastinal mass, which confirmed the presence of a carcinoid thymic tumor, the patient became totally asymptomatic, with normal ACTH and cortisol levels. A carcinoid thymic tumor has a poor prognosis, especially when it is associated with Cushing's syndrome. Most patients will present recidivism or metastasis within 5 years after surgery. However, the low number of cases available for analysis makes it difficult to establish optimum therapeutic approaches. {\textcopyright} 2009 Humana Press.",

keywords = "Carcinoid, Cushing's syndrome, Neuroendocrine tumors, Thymus",

author = "Cristina Claret and Chillar{\'o}n, {Juan J.} and Flores, {Juana A.} and David Benaiges and Rafael Aguil{\'o} and Mar Garc{\'i}a and Guadalupe Aguilar and Alberto Goday and Cano-P{\'e}rez, {Juan F.}",

year = "2010",

month = feb,

day = "1",

doi = "10.1007/s12020-009-9249-0",

language = "English",

volume = "37",

pages = "1--5",

number = "1",

}

Carcinoid tumor of the thymus associated with Cushing's syndrome and dysgeusia: Case report and review of the literature. / Claret, Cristina; Chillarón, Juan J.; Flores, Juana A.; Benaiges, David ; Aguiló, Rafael; García, Mar; Aguilar, Guadalupe; Goday, Alberto; Cano-Pérez, Juan F.

In: Endocrine, Vol. 37, No. 1, 01.02.2010, p. 1-5.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Carcinoid tumor of the thymus associated with Cushing's syndrome and dysgeusia: Case report and review of the literature

AU - Claret, Cristina

AU - Chillarón, Juan J.

AU - Flores, Juana A.

AU - Benaiges, David

AU - Aguiló, Rafael

AU - García, Mar

AU - Aguilar, Guadalupe

AU - Goday, Alberto

AU - Cano-Pérez, Juan F.

PY - 2010/2/1

Y1 - 2010/2/1

N2 - A 30-year-old man was hospitalized with edema, polyuria, and abnormalities in taste. ACTH and cortisol levels at admission were markedly elevated, even after attempted suppression with 8 mg dexamethasone. A thoracic-abdominal CT revealed an anterior mediastinal lesion and hyperplasia of both adrenal glands. After excision of the mediastinal mass, which confirmed the presence of a carcinoid thymic tumor, the patient became totally asymptomatic, with normal ACTH and cortisol levels. A carcinoid thymic tumor has a poor prognosis, especially when it is associated with Cushing's syndrome. Most patients will present recidivism or metastasis within 5 years after surgery. However, the low number of cases available for analysis makes it difficult to establish optimum therapeutic approaches. © 2009 Humana Press.

AB - A 30-year-old man was hospitalized with edema, polyuria, and abnormalities in taste. ACTH and cortisol levels at admission were markedly elevated, even after attempted suppression with 8 mg dexamethasone. A thoracic-abdominal CT revealed an anterior mediastinal lesion and hyperplasia of both adrenal glands. After excision of the mediastinal mass, which confirmed the presence of a carcinoid thymic tumor, the patient became totally asymptomatic, with normal ACTH and cortisol levels. A carcinoid thymic tumor has a poor prognosis, especially when it is associated with Cushing's syndrome. Most patients will present recidivism or metastasis within 5 years after surgery. However, the low number of cases available for analysis makes it difficult to establish optimum therapeutic approaches. © 2009 Humana Press.

KW - Carcinoid

KW - Cushing's syndrome

KW - Neuroendocrine tumors

KW - Thymus

U2 - 10.1007/s12020-009-9249-0

DO - 10.1007/s12020-009-9249-0

M3 - Article

VL - 37

SP - 1

EP - 5

IS - 1

ER -