© 2019, Springer Nature Switzerland AG. Cancer appears as a result of mutation of normal tissue cells. In this paper, we consider the initial stage of the cancer appearance and development. In particular, we study the conditions that are necessary for an initial fixation of the mutant cells in a patient tissue and their further successful development. In order to do this, we are using a reasonably simple mutation-selection model composed of two interacting populations, namely, the normal cells and the mutant cells. Conditions for persistence of the mutant cells are found.
|Title of host publication||Trends in Mathematics|
|Number of pages||5|
|Publication status||Published - 1 Jan 2019|