Brucellosis treated with rifampicin

J. Llorens-Terol, R. M. Busquets

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29 Citations (Scopus)

Abstract

14 children, aged between 15 months and 14 years, with brucellosis were treated with oral rifampicin only (20 mg/kg per day) for 3 weeks. Laboratory diagnosis depended on blood culture (positive for Brucella melitensis in 11 of the cases), serum agglutination, complement-fixation test, and Coombs's test. Response was good in each child, with fever clearing between the 2nd and 8th day. 2 children relapsed, but one relapse was probably a reinfection from contaminated cheese. Both children were given a further course of treatment (rifampicin and co-trimoxazole) which was successful. Despite the reasonably good results with rifampicin alone, it is advisable to combine the drug with co-trimoxazole when treating brucellosis.
Original languageEnglish
Pages (from-to)486-488
JournalArchives of Disease in Childhood
Volume55
Issue number6
DOIs
Publication statusPublished - 1 Jan 1980

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