Broadband 1H homodecoupled NMR experiments: Recent developments, methods and applications

Laura Castañar, Teodor Parella

    Research output: Contribution to journalReview articleResearchpeer-review

    91 Citations (Scopus)

    Abstract

    Copyright © 2015 John Wiley & Sons, Ltd. Broadband 1H homonuclear NMR spectra display resonances as collapsed singlets, therefore minimizing signal overlap and expediting spectral analysis. This review aims at presenting the most recent advances in pure shift NMR spectroscopy, with a particular emphasis to the Zangger-Sterk experiment. A detailed discussion about pulse sequence design, selectivity, sensitivity, spectral resolution and performance is provided. Finally, the implementation of the different reported strategies into traditional 1D and 2D NMR experiments is described while several practical applications are also reviewed. In recent years, a great interest in the development of new broadband 1H homonuclear decoupled techniques providing simplified JHH multiplet patterns has emerged again in the field of small molecule NMR. The resulting highly resolved 1H NMR spectra display resonances as collapsed singlets, therefore minimizing signal overlap and expediting spectral analysis. This review aims at presenting the most recent advances in pure shift NMR spectroscopy, with a particular emphasis to the Zangger-Sterk experiment. A detailed discussion about the most relevant practical aspects in terms of pulse sequence design, selectivity, sensitivity, spectral resolution and performance is provided. Finally, the implementation of the different reported strategies into traditional 1D and 2D NMR experiments is described while several practical applications are also reviewed.
    Original languageEnglish
    Pages (from-to)399-426
    JournalMagnetic Resonance in Chemistry
    Volume53
    Issue number6
    DOIs
    Publication statusPublished - 1 Jun 2015

    Keywords

    • BIRD
    • HOBB
    • HOBS
    • homonuclear decoupling
    • NMR spectroscopy
    • PSYCHE
    • pure shift NMR
    • Zangger-Sterk

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