Boron trifluoride-methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity

Sergey Miltsov, Vladimir Karavan, Alexandr Misharev, Julian Alonso-Chamarro, Mar Puyol

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

© 2015 Elsevier Ltd. All rights reserved. A boron trifluoride-methanol complex demonstrated remarkable deprotection selectivity against commonly used amino-protecting groups in the deacetylation of acetanilides and high sensitivity to the steric hindrance of substrates. The scope and limitations of the reaction were explored.
Original languageEnglish
Pages (from-to)641-644
JournalTetrahedron Letters
Volume57
Issue number6
DOIs
Publication statusPublished - 10 Feb 2016

Keywords

  • Acetanilides
  • Boron trifluoride
  • Deacetylation
  • Deprotection

Fingerprint Dive into the research topics of 'Boron trifluoride-methanol complex. Mild and powerful reagent for deprotection of acetylated amines. Scope and selectivity'. Together they form a unique fingerprint.

  • Cite this