Boron complexes of L-cysteine

Asensio González, Jaume Granell, Juan F. Piniella, Angel Alvarez-Larena

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)


The synthesis of diphenyl[(R)-thiazolidine-4-carboxylato-O,N]boron 4, 9- borabicyclo[3.3.1]non-9-yl[(R)-thiazolidine-4-carboxylato-O,N]boron 9, 9- borabicyclo[3.3.1]non-9-yl[S-methyl-(R)-cysteinato-O,N]boron 10, and 9- borabicyclo[3.3.1]non-9-yl[S-trityl-(R)-cysteinato-O,N]boron 11 with potential application in Boron Neutron Capture Therapy is reported. The preparation of two derivatives of 2-oxo-propanoic acid, diphenyl[2- benzylimino-2-oxopropanoato-O,N]boron 6 and dicyclohexyl[2-imino-2- oxopropanoato-O,N]boron 8 is described. Compound 6 represents the first example of a monocyclic unsaturated oxazaborolidine-5-one whose crystal structure has been determined.
Original languageEnglish
Pages (from-to)13313-13322
Issue number43
Publication statusPublished - 22 Oct 1998


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