Bone mass of a 113-year-old man

Leonardo Mellibovsky; Mariona Bustamante; Pau Lluch; Xavier Nogues; Daniel Grinberg; Susana Balcells; Adolfo Diez-Perez

doi:10.1093/gerona/62.7.794

Bone mass of a 113-year-old man

Leonardo Mellibovsky, Mariona Bustamante, Pau Lluch, Xavier Nogues, Daniel Grinberg, Susana Balcells, Adolfo Diez-Perez

Department of Medicine

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Abstract

Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers. Copyright 2007 by The Gerontological Society of America.

Original language	English
Pages (from-to)	794-795
Journal	Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume	62
Issue number	7
DOIs	https://doi.org/10.1093/gerona/62.7.794
Publication status	Published - 1 Jan 2007

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abstract = "Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers. Copyright 2007 by The Gerontological Society of America.",

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AU - Mellibovsky, Leonardo

AU - Bustamante, Mariona

AU - Lluch, Pau

AU - Nogues, Xavier

AU - Grinberg, Daniel

AU - Balcells, Susana

AU - Diez-Perez, Adolfo

PY - 2007/1/1

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AB - Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers. Copyright 2007 by The Gerontological Society of America.

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DO - 10.1093/gerona/62.7.794

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JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences

JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences

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