Bone mass of a 113-year-old man

Leonardo Mellibovsky, Mariona Bustamante, Pau Lluch, Xavier Nogues, Daniel Grinberg, Susana Balcells, Adolfo Diez-Perez

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Osteoporosis is a common disease that affects elderly people. Aging induces loss of bone density and quality resulting in a progressive incidence of fragility fractures. In this study, we report the bone density of one of the oldest men in the world and of several of his first-degree relatives, as well as a genetic screen of these cases. No fractures have been suffered by any of them, and their bone mineral density (BMD) values in terms of z score were normal or lightly decreased. Neither mutations at the longevity-related gene KLOTHO nor the Gly171Val mutation of LRP5 associated with high bone mass was detected in the two centenarian stepbrothers. Copyright 2007 by The Gerontological Society of America.
Original languageEnglish
Pages (from-to)794-795
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume62
Issue number7
DOIs
Publication statusPublished - 1 Jan 2007

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