Bilastine vs. hydroxyzine: Occupation of brain histamine H1-receptors evaluated by positron emission tomography in healthy volunteers

Medicine and Dentistry

• Histamine H1 Receptor 69%
• Receptor Occupancy 60%
• Sedation 50%
• Positron Emission Tomography 40%
• Placebo 40%
• Histamine Antagonist 30%
• Adverse Event 30%
• Psychomotor Performance 30%
• Therapeutic Procedure 20%
• Plasma 20%
• Age 10%
• Visual Analog Scale 10%
• Doxepin 10%
• Insula 10%
• Oral Drug Administration 10%
• Carbon 11 10%
• Somnolence 10%
• Sedative Agent 10%
• Incidence 10%
• Brain 10%
• Male 10%
• Cerebral Cortex 10%
• Amaurosis 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Bilastine 100%
• Histamine H1 Receptor 69%
• Hydroxyzine 60%
• Binding Potential 40%
• Adverse Event 30%
• Antihistaminic Agent 30%
• Normal Human 10%
• Doxepin 10%
• Carbon 11 10%
• Somnolence 10%
• Incidence 10%
• Blindness 10%