Research on schizophrenia has revealed a number of factors related to its etiology and its clinics: psychological, virological, metabolic, pathological, biochemical, genetic and environmental. Amongst the neurotransmitter systems disorders, dopamine and serotonin dysfunction are the most frequently mentioned in the literature; their interplay with other neurotransmitter substances, such as noradrenaline, GABA and glutamate, and also with some neuropeptides, should provide us a more integrated view of brain function. Neuroanatomical data have revealed ventricular enlargement and diminished frontal and temporal lobe volume in some patients. These findings are concentrated particularly in temporolimbic structures.
|Publication status||Published - 1 Dec 1998|