In a simple holographic model for QCD in which the Chern-Simons term is incorporated to take into account the QCD chiral anomaly, we show that baryons arise as stable solitons which are the 5D analogs of 4D skyrmions. Contrary to 4D skyrmions and previously considered holographic scenarios, these solitons have sizes larger than the inverse cut-off of the model, and therefore they are predictable within our effective field theory approach. We perform a numerical determination of several static properties of the nucleons and find a satisfactory agreement with data. We also calculate the amplitudes of "anomalous" processes induced by the Chern-Simons term in the meson sector, such as ω → π γ and ω → 3 π. A combined fit to baryonic and mesonic observables leads to an agreement with experiments within 16%. © 2008 Elsevier B.V. All rights reserved.