Nine patients with neoplasms working in Spanish factories utilizing asbestos are presented. Four had worked in thermal insulation companies, four in fiber cement, and one in automobile brakes. The average time of exposure to the mineral was 26 years. The tumors appeared, on the average, 38 years after beginning the job. All of the patients were men who smoked, with an average age of 59 years. The tumor was located in the respiratory system in seven cases (one in the larynx, four in the lung, and two in the pleura). The other two neoplasias were found in the peritoneum and in the upper third of the esophagus. Thoracic x ray revealed signs of pulmonary asbestosis (pleural calcification and/or lung fibrosis) in six of the nine cases. Ferruginous bodies in sputum were found in only one case; however, pathologic studies showed them to be present in the fibrotic areas of the lung in seven cases. Histopathologic studies performed in all of the patients, either by biopsy or necropsy, showed the following tumors in the respiratory system: an epidermoid carcinoma of the larynx, a bronchial epidermoid carcinoma, undifferentiated carcinoma, an adenocarcinoma, a bronchoalveolar carcinoma, a papilliferous pleural mesothelioma. An epidermoid carcinoma of the esophagus and a peritoneal mesothelioma were found in the gastrointestinal tract.
|Publication status||Published - 1 Jan 1977|