Arterial cerebral infarcts in sickle cell trait and antithrombin III deficiency

Pere Comas, Luis D’Olhaberriague, Merce López, Lluis Soler-Singla, Jordi Pascual, Arantxa Matali, Adolf Pou-Serradell

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Since September 1987, all patients under 46 years admitted to our Hospital with cerebral infarcts (Cl), the cause of which was unknown, have undergone complete hematological screening (partial thromboplastin time; prothrombin ratio; fibrinogen level; lupus anticoagulant activity; fibrinolytic capacity; proteins C and S; antilhrom- bin III; AT-III, and hemoglobin electrophoresis when indicated). In 2 out of 22 patients admitted in 1988, sickle cell trait and AT-III deficiency were the only abnormalities identified. We conclude that complete hematological screening should be carried out in every young patient with Cl when more common causes are not present. © 1991 S. Karger AG, Basel.
Original languageEnglish
Pages (from-to)168-170
JournalCerebrovascular Diseases
Issue number3
Publication statusPublished - 1 Jan 1991


  • Antithrombin III, deficiency of
  • Ischemic stroke in young
  • Sickle cell trait


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