Arterial cerebral infarcts in sickle cell trait and antithrombin III deficiency

Pere Comas, Luis D’Olhaberriague, Merce López, Lluis Soler-Singla, Jordi Pascual, Arantxa Matali, Adolf Pou-Serradell

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Since September 1987, all patients under 46 years admitted to our Hospital with cerebral infarcts (Cl), the cause of which was unknown, have undergone complete hematological screening (partial thromboplastin time; prothrombin ratio; fibrinogen level; lupus anticoagulant activity; fibrinolytic capacity; proteins C and S; antilhrom- bin III; AT-III, and hemoglobin electrophoresis when indicated). In 2 out of 22 patients admitted in 1988, sickle cell trait and AT-III deficiency were the only abnormalities identified. We conclude that complete hematological screening should be carried out in every young patient with Cl when more common causes are not present. © 1991 S. Karger AG, Basel.
Original languageEnglish
Pages (from-to)168-170
JournalCerebrovascular Diseases
Volume1
Issue number3
DOIs
Publication statusPublished - 1 Jan 1991

Keywords

  • Antithrombin III, deficiency of
  • Ischemic stroke in young
  • Sickle cell trait

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