Antimicrobial prophylaxis and postexposure

D. L. van Esso Arbolave, Rodrigo Gonzalo C. de Liria

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


In classical antimicrobial prophylaxis, preventive administration of antibiotics is given in order to avoid the development of an infectious disease. This can be applied various clinical situations. It is a therapy that is not free from debate and controversy. In this review we examine antimicrobial prophylaxis for seven clinical conditions: neonatal ophthalmia, human and animal bites, vesicoureteral reflux, renal pelvic dilatation, recurrent acute otitis media, bacterial endocarditis and rheumatic fever. Experience allows a critical review of the effectiveness and usefulness of the proposed guidelines. Not all recommended antibiotic prophylaxis guidelines have the same level of consensus in relation to its application. In postexposure prophylaxis immunoglobulins, vaccines or antibiotics are administered in order to prevent infection after exposure to an infectious agent. This section will deal with postexposure prophylaxis in case of exposure to the following bacteria: Neisseria meningitidis, Haemophilus influenzae type b, Bordetella pertussis or viruses: hepatitis B, hepatitis A, varicella and measles virus.
Original languageEnglish
Pages (from-to)66-74
JournalPediatria Integral
Issue number1
Publication statusPublished - 1 Feb 2010


  • Antimicrobial prophylaxis
  • Pediatrics
  • Postexposure prophylaxis


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