Antimicrobial activity of Pycnogenol®

Maria Angeles Calvo Torras, Carles Adelantado Faura, F. Schönlau, P. Rohdewald

    Research output: Contribution to journalArticleResearchpeer-review

    50 Citations (Scopus)


    Pycnogenol®, a standardized extract of Pinus pinaster bark, was tested for its antimicrobial activity against 23 different pathogenic prokaryotic (gram-positive and gram-negative) and eukaryotic (yeast and fungi) micro-organisms. Pycnogenol® inhibited the growth of all the tested microorganisms in minimum concentrations ranging from 20 to 250 μg/mL. Thus, Pycnogenol® in concentrations as low as 0.025% could counteract the growth of all the strains investigated in our study. These results conform with clinical oral health care studies describing the prevention of plaque formation and the clearance of candidiasis by Pycnogenol®. Copyright © 2005 John Wiley & Sons, Ltd.
    Original languageEnglish
    Pages (from-to)647-648
    JournalPhytotherapy Research
    Publication statusPublished - 1 Jul 2005


    • Anti-bacterial
    • Candida
    • Plaque
    • Pycnogenol


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