Anti-Ro/SSA antibodies and cardiac rhythm disturbances: Present and future perspectives

Irene Santos-Pardo, Roger Villuendas, Iñaki Salvador-Corres, Melania Martínez-Morillo, Alejandro Olivé, Antoni Bayes-Genis

Research output: Contribution to journalReview articleResearchpeer-review

7 Citations (Scopus)

Abstract

© 2014 Published by Elsevier Ireland Ltd. Several case reports, small case series, and original research papers have recently suggested that the action of certain auto-antibodies related to connective tissue diseases may be responsible for significant cardiac rhythm disturbances in adults. The relationship between anti-Ro/SSA antibodies and congenital complete atrioventricular block iswell recognizedinthe fetal heart. Herein we review the emerging evidences of the link to increased levels of anti-Ro/SSA antibodies with rhythm disorders of unknown originin the adult. Confirmation of this distinct etiology may eventually be the basis for new therapies.
Original languageEnglish
Pages (from-to)244-250
JournalInternational Journal of Cardiology
Volume184
Issue number1
DOIs
Publication statusPublished - 1 Jan 2015

Keywords

  • Anti-Ro/SSA
  • Cardiac rhythm disturbances
  • Pathogenesis

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