Anterior lens capsule strains during simulated accommodation in porcine eyes

Antonio Pellegrino, Harvey John Burd, Laura Pinilla Cortés, Justin Christopher D'Antin, Nik Petrinic, Rafael I. Barraquer, Ralph Michael

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    1 Citation (Scopus)

    Abstract

    © 2017 Elsevier Ltd Experimental protocols have been developed to measure the spatial variation of the mechanical strains induced in the lens capsule during ex vivo lens stretching. The paper describes the application of these protocols to porcine lenses. The deformations and mechanical strains developed in the anterior capsule during each experiment were determined using full field digital image correlation techniques, by means of a speckle pattern applied to the lens surface. Several speckling techniques and illumination methods were assessed before a suitable combination was found. Additional data on the cross section shape of the anterior lens surface were obtained by Scheimpflug photography, to provide a means of correcting for lens curvature effects in the determination of the strains developed in the plane of the capsule. The capsule strains in porcine lenses exhibit non-linear behaviour, and hysteresis during loading and unloading. Peripheral regions experience higher magnitude strains than regions near the lens pole. The paper demonstrates the successful application of a procedure to make direct measurements of capsule strains simultaneously with ex vivo radial lens stretching. This experimental technique is applicable to future investigations on the mechanical characteristics of human lenses.
    Original languageEnglish
    Pages (from-to)19-27
    JournalExperimental Eye Research
    Volume168
    DOIs
    Publication statusPublished - 1 Mar 2018

    Keywords

    • Accommodation
    • Lens capsule
    • Porcine lens
    • Strain

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  • Cite this

    Pellegrino, A., Burd, H. J., Pinilla Cortés, L., D'Antin, J. C., Petrinic, N., Barraquer, R. I., & Michael, R. (2018). Anterior lens capsule strains during simulated accommodation in porcine eyes. Experimental Eye Research, 168, 19-27. https://doi.org/10.1016/j.exer.2017.12.008