Several nursing studies recognise the existence of problems that are caused by a low academic performance at international level, as well as an increase in absenteeism and abandonment of the degree. Most of these studies have used art as an instrument of learning, demonstrating an increase in student knowledge and motivation. The objective of this study is to evaluate a teaching experience that includes Arts-Based-Learning of the pathophysiology and nursing care of the skin. A two-phase mixed design was used to evaluate the (definitive) intervention. In the first phase, the qualitative performance was explored, and in the second phase, the quantitative performance was evaluated. Results: showed a better assimilation of learning contents for those students for whom art has been used as a teaching methodology. A high level of satisfaction among students was also observed with this methodology. Regarding creative thinking, the EDICOS scale showed a high consistency in all dimensions. However, no significant gender-related differences were found. Students expressed that the observation and interpretation of art have provided them with an outline of the current situation, and a reflection of nursing care.