This article represents the combination of expert consensus on hypersensitivity reactions of distinct international scientific societies and the experience of our unit in the diagnosis of perioperative anaphylactic reactions. The appropriate management of perioperative anaphylaxis requires early diagnostic suspicion, based on the patient's symptoms. Immediate laboratory tests (serum tryptase and plasma histamine) are required to confirm the hypersensitivity reaction but should not interfere with the start of appropriate treatment. The drug of choice in severe anaphylactic reactions continues to be adrenalin. The anesthesiologist is responsible for instigating this first phase while subsequent investigation of the causative mechanism and the etiological agent is performed by allergists. Finally, a joint report based on the findings of the (immediate and late) studies and the patient's symptoms should be provided. This report should contain information on the results of tests, the drugs and/or substances identified as causing the reaction, and recommendations for future anesthesia. © 2013 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor.
- Neuromuscular blockers
- Skin tests