An inkjet-printed field-effect transistor for label-free biosensing

Mariana Medina-Sánchez; Carme Martínez-Domingo; Eloi Ramon; Arben Merkoçi

doi:https://doi.org/10.1002/adfm.201401180

An inkjet-printed field-effect transistor for label-free biosensing

Mariana Medina-Sánchez, Carme Martínez-Domingo, Eloi Ramon, Arben Merkoçi

Research output: Contribution to journal › Article › Research › peer-review

47 Citations (Scopus)

Abstract

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. A flexible, biological field-effect transistor (BioFET) for use in biosensing is reported. The BioFET is based on an organic thin-film transistor (OTFT) fabricated mainly by inkjet printing and subsequently functionalized with antibodies for protein recognition. The BioFET is assessed for label-free detection of a model protein, human immunoglobulin G (HIgG). It is characterized electrically to evaluate the contribution of each step in the functionalization of the OTFT and to detect the presence of the target protein. The fabrication, structure, materials optimization, electrical characteristics, and functionality of the starting OTFT and final BioFET are also discussed. Different materials are evaluated for the top insulator layer, with the aim of protecting the lower layers from the electrolyte and preserving the BioFET electrical performance.

Original language	English
Pages (from-to)	6291-6302
Journal	Advanced Functional Materials
Volume	24
DOIs	https://doi.org/10.1002/adfm.201401180
Publication status	Published - 29 Oct 2014

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title = "An inkjet-printed field-effect transistor for label-free biosensing",

abstract = "{\textcopyright} 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. A flexible, biological field-effect transistor (BioFET) for use in biosensing is reported. The BioFET is based on an organic thin-film transistor (OTFT) fabricated mainly by inkjet printing and subsequently functionalized with antibodies for protein recognition. The BioFET is assessed for label-free detection of a model protein, human immunoglobulin G (HIgG). It is characterized electrically to evaluate the contribution of each step in the functionalization of the OTFT and to detect the presence of the target protein. The fabrication, structure, materials optimization, electrical characteristics, and functionality of the starting OTFT and final BioFET are also discussed. Different materials are evaluated for the top insulator layer, with the aim of protecting the lower layers from the electrolyte and preserving the BioFET electrical performance.",

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AU - Medina-Sánchez, Mariana

AU - Martínez-Domingo, Carme

AU - Ramon, Eloi

AU - Merkoçi, Arben

PY - 2014/10/29

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AB - © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. A flexible, biological field-effect transistor (BioFET) for use in biosensing is reported. The BioFET is based on an organic thin-film transistor (OTFT) fabricated mainly by inkjet printing and subsequently functionalized with antibodies for protein recognition. The BioFET is assessed for label-free detection of a model protein, human immunoglobulin G (HIgG). It is characterized electrically to evaluate the contribution of each step in the functionalization of the OTFT and to detect the presence of the target protein. The fabrication, structure, materials optimization, electrical characteristics, and functionality of the starting OTFT and final BioFET are also discussed. Different materials are evaluated for the top insulator layer, with the aim of protecting the lower layers from the electrolyte and preserving the BioFET electrical performance.

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