Amyotrophic lateral sclerosis

J. Martí-Fàbregas, J. Pradas

Research output: Contribution to journalReview articleResearchpeer-review

1 Citation (Scopus)


Several aspects of amyotrophic lateral sclerosis are reviewed, with special emphasis on arguments based on etiological and pathogenic theories currently in vogue: free radicals, glutamate-induced toxic excitation, trophic factors, autoimmunity and axon transport. Each of these theories has inspired therapeutic trials, some of which are already completed and others are still in progress. More than one neurodegenerative mechanism may be involved in amyotrophic lateral sclerosis, meaning that it might be necessary to combine several drugs in future trials.
Original languageEnglish
Pages (from-to)99-108
Issue number3
Publication statusPublished - 1 Mar 1996


  • amyotrophic lateral sclerosis


Dive into the research topics of 'Amyotrophic lateral sclerosis'. Together they form a unique fingerprint.

Cite this