Amine oxidase activities in bovine lung.

J. M. Lizcano, D. Balsa, K. F. Tipton, M. Unzeta

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Abstract

The subcellular distributions of amine oxidase activities MAO-A, MAO-B and SSAO, in bovine lung have been determined. MAO activities are largely confined to the mitochondria whereas SSAO activity is concentrated in the microsomal fraction. The contribution of different type of amine oxidase present in the microsomal fraction to the metabolism of the benzylamine, tyramine, phenylethylamine, tryptamine and dopamine were determined. The kinetic constants towards benzylamine showed SSAO to have a higher affinity than MAO-B, and the comparison of the Vmax/Km relationship for both enzymes indicated that benzylamine would be oxidised more efficiently by SSAO than by MAO-B.
Original languageEnglish
Pages (from-to)341-344
JournalJournal of neural transmission. Supplementum
Volume32
Publication statusPublished - 1 Jan 1990

Fingerprint

Dive into the research topics of 'Amine oxidase activities in bovine lung.'. Together they form a unique fingerprint.

Cite this