TY - JOUR
T1 - Alcohol use disorder and cognitive impairment in old age patients: A 6 months follow-up study in an outpatient unit in Barcelona
AU - Ros-Cucurull, Elena
AU - Palma-Álvarez, Raúl Felipe
AU - Cardona-Rubira, Cristina
AU - García-Raboso, Elena
AU - Jacas, Carlos
AU - Grau-López, Lara
AU - Abad, Alfonso Carlos
AU - Rodríguez-Cintas, Laia
AU - Ros-Montalbán, Salvador
AU - Casas, Miguel
AU - Ramos-Quiroga, Josep Antoni
AU - Roncero, Carlos
PY - 2018/3/1
Y1 - 2018/3/1
N2 - © 2018 Elsevier B.V. There has been little research about deleterious effects, including cognitive impairment, related to hazardous long-term alcohol use in old adults. This study aims to assess cognitive decline in old patients with alcohol use disorder and changes in cognitive state at 6 months follow-up, achieving or not abstinence. A six-month follow-up study was conducted in an outpatient center in Barcelona on a sample of old adults (≥65 years old) who had hazardous alcohol use. The sample was compared with healthy volunteers adjusted for age, sex and years of education. A neuropsychological protocol was performed at baseline and after 6 months follow-up covering four cognitive domains: attention, visuospatial abilities, memory and executive functions. Several domains were significant impaired at baseline: visual immediate and delayed recall, working memory, immediate verbal learning, total words learned, set switching and sustained attention. At 6 months reassessment, alcohol abstinence was achieved in 93.5% of patients and it was detected a trend towards improvement in direct mean scores of all cognitive areas, although it was not significant. The current study points out a cognitive impairment in many areas secondary to alcohol long-term hazardous use in old adults. A trend towards cognitive improvement after recovery was detected in most patients.
AB - © 2018 Elsevier B.V. There has been little research about deleterious effects, including cognitive impairment, related to hazardous long-term alcohol use in old adults. This study aims to assess cognitive decline in old patients with alcohol use disorder and changes in cognitive state at 6 months follow-up, achieving or not abstinence. A six-month follow-up study was conducted in an outpatient center in Barcelona on a sample of old adults (≥65 years old) who had hazardous alcohol use. The sample was compared with healthy volunteers adjusted for age, sex and years of education. A neuropsychological protocol was performed at baseline and after 6 months follow-up covering four cognitive domains: attention, visuospatial abilities, memory and executive functions. Several domains were significant impaired at baseline: visual immediate and delayed recall, working memory, immediate verbal learning, total words learned, set switching and sustained attention. At 6 months reassessment, alcohol abstinence was achieved in 93.5% of patients and it was detected a trend towards improvement in direct mean scores of all cognitive areas, although it was not significant. The current study points out a cognitive impairment in many areas secondary to alcohol long-term hazardous use in old adults. A trend towards cognitive improvement after recovery was detected in most patients.
KW - Alcohol use
KW - Cognitive impairment
KW - Executive functions
KW - Neuropsychology
KW - Old adults
U2 - 10.1016/j.psychres.2017.12.069
DO - 10.1016/j.psychres.2017.12.069
M3 - Article
VL - 261
SP - 361
EP - 366
JO - Psychiatry Research
JF - Psychiatry Research
SN - 0165-1781
ER -