Age-stratified analysis of I-PSS and Qol values in spanish patients with symptoms potentially related to BPH

Remigio Vela-Navarrete, V. Alfaro, L. L. Badiella, N. Fernández-Hernando

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    12 Citations (Scopus)


    Objective: The main goal of the present study was to determine age-related symptom changes using a validated Spanish International Prostate Symptom Score (I-PSS) and quality of life index (QoL) in Spanish patients with symptomatic benign prostatic hyperplasia (BPH). Methods: A total of 2,875 patients with the clinical diagnosis of symptomatic BPH were evaluated. Data were collected during current medical practice in a national study. Patients were excluded if they had any previous prostate operation or suspicion of prostate cancer. I-PSS was self- administered and compared with the physician's global impression. Results: I-PSS symptoms, both voiding and storage symptoms, increased significantly with age (p<0.0001) as well as QoL (p<0.0017). A change in the I-PSS categories (minor, moderate and severe) was found with age, increasing severe symptomatic patients in the oldest groups. A significant correlation was found between I-PSS and QoL (r = 0.49, p<0.001), being this relationship linear and not significantly influenced by age. Conclusions: This study confirms reliable results using a validated Spanish I-PSS in a large national representative sample of Spanish patients with BPH symptoms. The age-stratified analysis showed that the natural progression of BPH with age was related to an increased symptomatology and bothersomeness, well reflected by increases in the I-PSS and QoL values. Nevertheless, the effect of symptomatology on quality of life was not strongly influenced by the age of the patient. Copyright (C) 2000 S. Karger AG, Basel.
    Original languageEnglish
    Pages (from-to)199-207
    JournalEuropean Urology
    Issue number2
    Publication statusPublished - 1 Jan 2000


    • Age
    • Benign prostatic hyperplasia
    • Elderly
    • I-PSS
    • Prostate
    • QoL
    • Quality of life


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