Age-dependency in host-vector models: The global analysis

Cruz Vargas-De-León, Lourdes Esteva, Andrei Korobeinikov

    Research output: Contribution to journalArticleResearchpeer-review

    20 Citations (Scopus)

    Abstract

    In this paper, we introduce and analyze two structured models for the transmission of a vector-borne infectious disease. The first of these models assumes that the level of contagiousness and the rate of removal (recovery) of infected hosts depends on the infection age. In the second model the hosts population is structured with respect to the physical age of the hosts, and the susceptibility of the hosts is assumed to be age-dependent. For these models, the threshold parameter for the existence of a positive (endemic) equilibrium state is determined, and the global asymptotic stability of the equilibrium states are established by the Lyapunov's direct method. © 2014 Elsevier Inc. All rights reserved.
    Original languageEnglish
    Pages (from-to)969-981
    JournalApplied Mathematics and Computation
    Volume243
    DOIs
    Publication statusPublished - 15 Sep 2014

    Keywords

    • Age-dependent susceptibility
    • Direct Lyapunov method
    • Global stability
    • Host-vector model
    • Infection-age dependent infectivity
    • Vector-borne infection

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