Acromegaly and the Vascular System

Eugenia Resmini, Susan M. Webb

Research output: Chapter in BookChapterResearchpeer-review

Abstract

© 2015 Springer-Verlag Berlin Heidelberg, All rights reserved. Acromegaly is due to long-term exposure to elevated levels of GH and IGF-I. The high prevalence of cardiac complications is the main cause of increased mortality, especially in active disease. The most common feature is a concentric biventricular hypertrophy; however, arrhythmias, diastolic followed by systolic dysfunction, valve disease, hypertension, and endothelial dysfunction may also be present. Control of the disease can improve cardiovascular morbidity and therefore reduce cardiovascular mortality.
Original languageEnglish
Title of host publicationPanVascular Medicine, Second Edition
Pages4627-4633
Number of pages6
DOIs
Publication statusPublished - 1 Jan 2015

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