Acquisition and diffusion of bla<inf>CTX-M-9</inf> gene by R478-IncHI2 derivative plasmids

Aurora García; Ferran Navarro; Elisenda Miró; Laura Villa; Beatriz Mirelis; Pere Coll; Alessandra Carattoli

doi:10.1111/j.1574-6968.2007.00695.x

Acquisition and diffusion of bla<inf>CTX-M-9</inf> gene by R478-IncHI2 derivative plasmids

Aurora García, Ferran Navarro, Elisenda Miró, Laura Villa, Beatriz Mirelis, Pere Coll, Alessandra Carattoli

Department of Genetics and Microbiology

Research output: Contribution to journal › Article › Research › peer-review

47 Citations (Scopus)

Abstract

Escherichia coli and Salmonella enterica isolates carrying the bla CTX-M-9 gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996-1999 period. The bla CTX-M-9-carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of the present work was to identify and better characterize the plasmids involved in the spread of the blaCTX-M-9 gene. Results showed that the majority of these strains carried plasmids belonging to the IncHI2 incompatibility group. The IncHI2 plasmids were further characterized, and found to be related to the reference IncHI2 plasmid R478. © 2007 Federation of European Microbiological Societies.

Original language	English
Pages (from-to)	71-77
Journal	FEMS Microbiology Letters
Volume	271
Issue number	1
DOIs	https://doi.org/10.1111/j.1574-6968.2007.00695.x
Publication status	Published - 1 Jun 2007

Keywords

Antimicrobial resistance
ESBL
Mechanisms of resistance
Mobile elements

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title = "Acquisition and diffusion of blaCTX-M-9 gene by R478-IncHI2 derivative plasmids",

abstract = "Escherichia coli and Salmonella enterica isolates carrying the bla CTX-M-9 gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996-1999 period. The bla CTX-M-9-carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of the present work was to identify and better characterize the plasmids involved in the spread of the blaCTX-M-9 gene. Results showed that the majority of these strains carried plasmids belonging to the IncHI2 incompatibility group. The IncHI2 plasmids were further characterized, and found to be related to the reference IncHI2 plasmid R478. {\textcopyright} 2007 Federation of European Microbiological Societies.",

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author = "Aurora Garc{\'i}a and Ferran Navarro and Elisenda Mir{\'o} and Laura Villa and Beatriz Mirelis and Pere Coll and Alessandra Carattoli",

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T1 - Acquisition and diffusion of blaCTX-M-9 gene by R478-IncHI2 derivative plasmids

AU - García, Aurora

AU - Navarro, Ferran

AU - Miró, Elisenda

AU - Villa, Laura

AU - Mirelis, Beatriz

AU - Coll, Pere

AU - Carattoli, Alessandra

PY - 2007/6/1

Y1 - 2007/6/1

N2 - Escherichia coli and Salmonella enterica isolates carrying the bla CTX-M-9 gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996-1999 period. The bla CTX-M-9-carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of the present work was to identify and better characterize the plasmids involved in the spread of the blaCTX-M-9 gene. Results showed that the majority of these strains carried plasmids belonging to the IncHI2 incompatibility group. The IncHI2 plasmids were further characterized, and found to be related to the reference IncHI2 plasmid R478. © 2007 Federation of European Microbiological Societies.

AB - Escherichia coli and Salmonella enterica isolates carrying the bla CTX-M-9 gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996-1999 period. The bla CTX-M-9-carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of the present work was to identify and better characterize the plasmids involved in the spread of the blaCTX-M-9 gene. Results showed that the majority of these strains carried plasmids belonging to the IncHI2 incompatibility group. The IncHI2 plasmids were further characterized, and found to be related to the reference IncHI2 plasmid R478. © 2007 Federation of European Microbiological Societies.

KW - Antimicrobial resistance

KW - ESBL

KW - Mechanisms of resistance

KW - Mobile elements

U2 - 10.1111/j.1574-6968.2007.00695.x

DO - 10.1111/j.1574-6968.2007.00695.x

M3 - Article

VL - 271

SP - 71

EP - 77

IS - 1

ER -

Acquisition and diffusion of bla<inf>CTX-M-9</inf> gene by R478-IncHI2 derivative plasmids

Abstract

Keywords

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