Accurate measurement of J<inf>HH</inf> in overlapped signals by a TOCSY-edited SERF Experiment

André Fredi, Pau Nolis, Teodor Parella

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Abstract

Copyright © 2016 John Wiley & Sons, Ltd. Selective refocusing (GSERF or the recent PSYCHEDELIC) experiments were originally designed to determine all proton–proton coupling constants (JHH) for a selected proton resonance. They work for isolated signals on which selective excitation can be successfully applied but, as it happens in other selective experiments, fail for overlapped signals. To circumvent this limitation, a doubly-selective TOCSY-GSERF scheme is presented for the measurement of JHH in protons resonating in crowded regions. This new experiment takes advantage of the editing features of an initial TOCSY transfer to uncover hidden resonances that become accessible to perform the subsequent frequency-selective refocusing. Copyright © 2016 John Wiley & Sons, Ltd.
Original languageEnglish
Pages (from-to)525-529
JournalMagnetic Resonance in Chemistry
Volume55
Issue number6
DOIs
Publication statusPublished - 1 Jun 2017

Keywords

  • GSERF
  • J-resolved
  • PSYCHE
  • PSYCHEDELIC
  • proton–proton coupling constants
  • selective TOCSY

Fingerprint Dive into the research topics of 'Accurate measurement of J<inf>HH</inf> in overlapped signals by a TOCSY-edited SERF Experiment'. Together they form a unique fingerprint.

  • Cite this