Abstract
© 2018 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. The mechanism of a trinuclear cooperative dehydrogenative C−N bond-forming reaction is investigated in this work, which avoids the use of chelate-assisting directing groups. Two new highly efficient Ru/Cu co-catalyzed systems were identified, allowing orders of magnitude greater TOFs than the previous state of the art. In-depth kinetic studies were performed in combination with advanced DFT calculations, which reveal a decisive rate-determining trinuclear Ru–Cu cooperative reductive elimination step (CRE).
Original language | English |
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Pages (from-to) | 15178-15184 |
Journal | Chemistry - A European Journal |
Volume | 24 |
DOIs | |
Publication status | Published - 12 Oct 2018 |
Keywords
- cooperative reductive elimination
- cross dehydrogenative coupling
- C−H bond activation
- dehydrogenative amination
- trinuclear catalysis