Several title compounds have been synthesized from D-mannitol as the unique chiral precursor. The target molecules include pairs of enantiomers and their configuration has mainly been assured by controlling the facial and the endo/exo diastereoselectivity in the Diels-Alder reactions of chiral cyclic or acyclic dienophiles. Some of the products obtained are key intermediates in the synthesis of biologically active compounds. © 1993.
|Publication status||Published - 1 Jan 1993|